Loryna (drospirenone / ethinyl estradiol) is a once-daily oral contraceptive used to prevent pregnancy. It is the generic form of Yaz. Both medications contain drospirenone, a new type of synthetic hormone that has recently been linked to a 75% increased risk of developing a blood clot. The pharmaceutical company Bayer is now facing more than 11,000 lawsuits brought by women who have suffered a life-threatening blood clot, heart attack, stroke, pulmonary embolism, deep vein thrombosis, or death after taking birth control pills containing drospirenone, including Loryna.
Loryna is an oral birth control pill containing the following active ingredients:
- 3-mg drospirenone
- 0.02-mg ethinyl estradiol
Loryna was approved by the U.S. Food and Drug Administration (FDA) in 2011. Loryna is indicated for the prevention of pregnancy, and also for the treatment of moderate acne and premenstrual dysphoric disorder (PMDD).
Loryna is the second generic version of Yaz (the other is Gianvi). All three medications contain the same active ingredients, and have the same dosage, risks, benefits, and side effects. The biggest difference is that all three products are sold by different companies. Loryna is sold by the generic drug company Sandoz Pharmaceuticals.
Loryna and Drospirenone
Another similarity between Loryna, Yaz, and Gianvi is they all contain drospirenone, a newly-developed synthetic version of the female reproductive hormone progestin. All birth control pills that contain progestin slightly increase the risk of blood clots. However, there is a growing body of scientific evidence linking drospirenone to a higher risk of blood clots than other synthetic progestin.
In 2011, the FDA warned that women taking drospirenone may be 75% more likely to develop a blood clot. In real numbers, the absolute risk appears small — roughly 10 per 10,000 women taking the medication are expected to have a blood clot. Though there are greater risks with drospirenone, it is equally effective at preventing pregnancy. Given this information, most women would probably choose the less risky medication. However, after Bayer ran a massive advertising campaign for Yaz, tens of millions of women switched to a drospirenone-containing birth control pill. Thus, a slightly increased risk of blood clots became tens of thousands of cases.
Loryna and Blood Clots
In some women, the drospirenone in Loryna causes potassium levels to increase too much in the bloodstream. This increases the risk of developing a blood clot in veins deep inside the body, in a condition known as Deep Vein Thrombosis. The problem with DVT is that, sometimes, these blood clots break loose and begin to travel in the bloodstream. This is called an embolism. Once a blood clot is in the bloodstream, it will travel until it becomes trapped in a major organ. A blood clot that forms in the lower part of the body will be pumped into the lungs. Inside the lungs, the blood vessels get gradually narrower and narrower until the blood clot becomes trapped. The lung tissue that is behind the blood clot is quickly deprived of oxygen and begins to die. This is called a pulmonary embolism, and around 30% of untreated cases lead to death.
Blood clots that form in other areas of the body can also be pumped to the heart, brain, or other major internal organs. If the blood clots become trapped in these organs, they can cause heart attack, ischemic stroke, organ damage or failure, and death.
Loryna Side Effects
The most severe side effect of Loryna is death
If you have suffered any of the following side effects after using Loryna, you have likely incurred extreme physical pain and suffering, emotional anguish, medical expenses, lost income. You may also have a permanent disability that impairs your quality of life. If you are a family member of a woman who died after taking Loryna, you are likely seeking justice from the pharmaceutical company responsible for side effects of the medication your loved one was using. You have a legal right to seek justice and compensation for your injury.
Side effects of Loryna may include, but are not limited to:
- Blood clots
- Deep vein thrombosis (DVT)
- Venous thromboembolism (VTE)
- Pulmonary embolism (PE)
- Hyperkalemia (toxic high levels of potassium in the bloodstream, which can cause irregular heartbeat and sudden death)
- Abnormal heart rhythm
- Heart attack (myocardial infarction)
- Gallbladder damage or failure