Call Today for a FREE Confidential Case Review
Toll-Free 24/7 (866) 920-0753

Depo-Testosterone Blood Clot


Blood clots in the legs are a possible side effect of Depo-Testosterone and other testosterone replacement products. They can occur at any time during treatment, but are most common in the first few months. Blood clots can cause life-threatening complications, such as heart attack, pulmonary embolism, and stroke.

Depo-Testosterone Blood Clots

Depo-Testosterone is an intramuscular injection of testosterone cypionate. It is used to treat hypogonadism (low testosterone) in males. Like all testosterone replacement products, Depo-Testosterone can potentially elevate a man’s risk of blood clots in the legs (also known as deep vein thrombosis or DVT).

How Does Testosterone Increase the Risk of Blood Clots?

Testosterone increases production of a kidney hormone called erythropoietin, which triggers bone marrow to make more red blood cells. These extra cells thicken the blood and make it harder to pump, which forces the heart to elevate blood pressure. These effects can all increase the risk of blood clots in the legs, a condition also known as deep vein thrombosis (DVT).

What is a Blood Clot?

Blood clots are sticky, semi-solid coagulations of red blood cells, platelets, clotting factors, and other substances in the blood. When they grow in arteries or veins, they are called a thrombus. When they travel in the bloodstream, they are called an embolism.


  • Heart attack
  • Stroke
  • Pulmonary embolism
  • Post-thrombotic syndrome
  • Kidney damage
  • Right-sided heart failure
  • Bone death (osteonecrosis)
  • Blindness
  • Organ damage
  • Amputation of a part or all of the leg
  • Death


Call 911 and seek emergency medical attention if you think you have a blood clot. In many cases, blood clots dissolve spontaneously without causing complications. However, they can be deadly. Hospitals typically treat blood clots by administering an intravenous “clot-busting” drug (heparin, for example). In serious cases, doctors may use catheter techniques, surgery, or implant a filter to catch blood clots before they enter the lungs.

Additional Information


Free Case Evaluation

The Schmidt Firm, PLLC has been recognized as one of the nation’s leading plaintiffs' law firms and handles cases in all 50 states. We are very proud of our legal achievements, but equally self-respecting of our firm's reputation for providing personal attention to each and every client we represent.

No matter what type of case you have, you may contact us with confidence by filling out the email contact form below or calling us directly by dialing toll free 24 hrs/day (866) 920-0753.