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Dexilant Acute Interstitial Nephritis

Dexilant Acute Interstitial Nephritis

Acute interstitial nephritis (kidney inflammation) is a side effect of all anti-heartburn drugs in the Proton-Pump Inhibitor (PPI) class, including Dexilant.

What You Can Do & How We Can Help

The Schmidt Firm, PLLC is currently accepting Dexilant induced injury cases in all 50 states. If you or somebody you know has been diagnosed with acute interstitial nephritis, you should contact our lawyers immediately for a free case consultation. Please use the form below to contact our Defective Drug Litigation Group or call toll free 24 hours a day at (866) 920-0753.

Overview

Dexilant is the brand-name for dexlansoprazole, a prescription medicine that decreases the amount of stomach acid. It is closely related to Prevacid (lansoprazole).

What is the problem?

Patients on Dexilant can develop acute interstitial nephritis, a side effect that is caused by an allergic reaction when the kidneys are cleaning the blood. The spaces between tubules suddenly becomes inflamed and swollen, which decreases kidney function and causes health problems.

FDA Updates Warnings for Dexilant

The label on Dexilant was updated by the FDA to include acute interstitial nephritis in December 2015. However, evidence of this side effect has been growing since the 1990s, when the first case reports were linked to PPIs.

Study Finds 3X Risk of Nephritis

A study published by Canadian researchers in CMAJ Open found a 3X increased risk of acute interstitial nephritis among PPI users. The conclusions were based on 290,000 adults over 66 years old who lived in Ontario.

Symptoms of Interstitial Nephritis

  • Fever
  • Urine has blood or pus (may be cloudy or pink)
  • Pain in the kidneys, stomach area, or pelvis
  • Swelling due to fluid-retention
  • Decreased or increased urination
  • Nausea and vomiting
  • Rash
  • Confusion
  • High blood pressure
  • And more

How is Nephritis Treated?

It often takes a few weeks or months before patients are sick enough to seek treatment. The first step in treatment is discontinuing Dexilant. Patients also must be hospitalized to receive anti-inflammatory corticosteroids and intravenous (IV) fluids. The problem is that delayed treatment increases the risk of complications like Chronic Kidney Disease (CKD), End-Stage Renal Disease (ESRD), or kidney failure.

Do I have a Dexilant Lawsuit?

The Schmidt Firm, PLLC is currently accepting Dexilant induced injury cases in all 50 states. If you or somebody you know has been diagnosed with acute interstitial nephritis, you should contact our lawyers immediately for a free case consultation. Please use the form below to contact our Defective Drug Litigation Group or call toll free 24 hours a day at (866) 920-0753.

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