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Janumet Thyroid Cancer Complications

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Most people have a very low risk of Janumet thyroid cancer complications. This is because thyroid cancer is usually slow-growing and can be removed with surgery. However, because the thyroid gland is located in the neck, complications of surgery or an aggressive tumor may include voice box paralysis, nerve damage, metastasis (spread) of the cancer, lifelong hormone supplement medications, and more.


Most people have a very low risk of Janumet thyroid cancer complications. Thyroid cancer is very rare, Janumet has only been linked to a couple possible cases, and most types of cancer are slow-growing (only 1% of people with thyroid cancer have aggressive anaplastic thyroid cancer).

Janumet works by influencing a hormone called GLP-1. Another anti-diabetes medication that influences GLP-1 is liraglutide, which has been shown to cause proliferation of cancerous thyroid C-cell tumors. This is a risk factor for medullary thyroid cancer, a slow-growing variety that is usually diagnosed and removed surgically before it causes severe complications.

Like all cancers, the most serious possible Janumet thyroid cancer complication is metastasis (spread of the cancer to other organs or tissues). Thyroid cancer is most likely to spread to the lungs, bones, and lymph nodes, but it can also spread to other areas of the body.

Thyroid Cancer Surgery Complications

Thyroid cancer surgery complications can be very serious and cause permanent injuries. The thyroid gland is located in the lower-front and center of the neck, close to the windpipe, larynx (voice box), nerves, major blood vessels, and more. These can all be damaged during a thyroid cancer surgery called a thyroidectomy (removal of all or part of the thyroid gland). Furthermore, if hormone-producing thyroid cells are removed, the patient may require lifelong hormone supplement treatments.

One serious Janumet thyroid cancer complication is voice box paralysis, which occurs when nerves are damaged during removal of the thyroid gland. It can also occur if the tumor is aggressive and grows into tissues in the neck. These complications include:

  • Abnormal tone of voice
  • Decreased speaking ability
  • Quiet or “breathy” sound to the voice
  • Hoarseness
  • Need for many breaths while speaking
  • Breathing is noisy or wheezing

Thyroid Cancer Recurrence

Even with prompt diagnosis and treatment, Janumet thyroid cancer complications can return. Thyroid cancer can recur in thyroid tissues that are not removed surgically. Cancerous cells can also cause malignancies in other areas of the body (such as the lymph nodes), which is why lifelong follow-up care is necessary to check for recurrent thyroid cancer.

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