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Pristiq During First Trimester of Pregnancy and Birth Defects

Pristiq During First Trimester of Pregnancy and Birth Defects

November 20, 2012 — Pristiq (desvenlafaxine), an antidepressant medication, may increase your risk of having a baby with a birth defect if it is taken during the first trimester of pregnancy. Pristiq treats depression by targeting serotonin and norepinephrine, two neurotransmitters that influence mood and emotions. Serotonin is also very important during fetal development, and any disruption to the fetal serotonin signaling could potentially cause a life-threatening birth defect.

During the first trimester of pregnancy (until the fetus is 12 weeks old), a fertilized egg divides into millions of cells that grow into physical structures. Serotonin appears very early in fetal development. It is an important signaling molecule involved in cell proliferation, differentiation, migration, and death.

When a pregnant woman uses Pristiq, the drug dissolves in her bloodstream and passes to her developing baby through the placenta. Experts do not fully understand how antidepressants influence fetal brain development or physical development. However, some experts have hypothesized that its effects on serotonin provide “biological plausibility for the origin of heart defects.”

The study, which was published in the medical journal Reproductive Toxicology in December 2011, found that serotonin was an important signaling molecule in fetal heart development:

“Serotonin may be particularly important for heart development and evidence suggests that from the time that progenitor heart cells are patterned during the establishment of laterality, to formation of the outflow tract, to myocardial cell differentiation, to septation of the heart chambers, the neurotransmitter may act as an important signaling molecule.”

The researchers claimed that the use of an antidepressant during the first trimester could potentially increase the risk of having a baby with a birth defect.

Many women who used Pristiq during the first trimester did not know about studies linking Pristiq to birth defects. Some of these women are now seeking justice by filing a Pristiq lawsuit. If you took Pristiq during the first trimester of pregnancy and had a baby with a birth defect, you could potentially qualify for compensation for your child’s injury, medical expenses, future care, and more.

Do I have a Pristiq Lawsuit?

The Schmidt Firm, PLLC is currently accepting Pristiq induced injury cases in all 50 states. If you or somebody you know took Pristiq during pregnancy and had a baby with a birth defect, you should contact our lawyers immediately for a free case consultation. Please use the form below to contact our Product Liability & Defective Drug Litigation Group or call toll free 24 hours a day at (866) 920-0753.

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