The heartburn drug Aciphex has been linked to an increased risk of kidney inflammation (nephritis), renal disease, bone fractures, stomach cancer, and other severe side effects.
What You Can Do & How We Can Help
The Schmidt Firm, PLLC is currently accepting Aciphex induced injury cases in all 50 states. If you or somebody you know was diagnosed with kidney failure or another severe side effect, you should contact our lawyers immediately for a free case consultation. Please use the form below to contact our Defective Drug Litigation Group or call toll free 24 hours a day at (866) 920-0753.
Heartburn Drugs and Stomach Cancer
In November 2017, a study published in the journal Gut found a doubled (2X) higher risk of stomach cancer for people who were on long-term treatment with heartburn medications in the Proton Pump Inhibitor (PPI) class, which includes popular antacids like Aciphex.
Aciphex Lawsuits Centralized in MDL
August 2017 — Judges have centralized 161 lawsuits involving kidney injuries from Aciphex and other PPI heartburn drugs into Multi-District Litigation (MDL No. 2798) under Judge Claire C. Cecchi in the District of New Jersey — In RE: Proton-Pump Inhibitor Products Liability Litigation (No. II). Drug-makers are accused of failing to warn that Aciphex cause kidney injuries, Chronic Kidney Disease (CKD), acute interstitial nephritis, end-stage kidney disease, or kidney failure.
Study: Heartburn Drugs Increase Risk of Death
July 2017 — Researchers have linked the use of PPI heartburn drugs with up to a 50% increased risk of death compared to H2-blocker heartburn drugs, according to a study published in the journal BMJ Open. The researchers estimated 1 excess death per 500 people who take a PPI. Click here to read more.
Heartburn Drugs Causing Massive Health Problems
Study Links Aciphex and Kidney Failure
April 2016 — The Journal of the American Society of Nephrology has published a study linking long-term use of antacid medications like Aciphex with a 96% increased risk of kidney failure and a 26% increased risk of chronic kidney disease. Click here to read more.
What is Aciphex?
Aciphex (rabeprazole) is a type of drug known as a Proton Pump Inhibitor (PPI). It is manufactured by Eisai Co. and distributed by Janssen Pharmaceuticals. Inc.
Aciphex drug is used in the treatment of diseases that are caused when the stomach produces too much acid. Most people take Aciphex for heartburn, otherwise known as gastroesophageal reflux disease (GERD). This painful condition occurs when stomach acid overflows into the esophagus. By reducing the amount of stomach acid, Aciphex allows the body to heal damaged tissue in the esophagus or ulcers in the stomach.
Aciphex and Kidney Damage
In December 2014, the FDA updated the label on Aciphex to include stronger warnings about acute interstitial nephritis. It causes sudden swelling and inflammation in the kidneys due to an allergic reaction to Aciphex. Without treatment, it can lead to kidney failure.
In January 2016, researchers at Johns Hopkins published a study linking PPIs with higher rates of Chronic Kidney Disease (CKD). According to investigators, people who use PPIs once-daily or twice-daily face a 20-50% increased risk of kidney disease. This progressive condition damages the kidneys, reduces their ability to clean the blood, and can lead to kidney failure.
In April 2015, PPIs were linked to acute kidney injury and nephritis in a study published by the medical journal CMAJ Open. Researchers analyzed data on 290,000 older adults in Ontario who started taking PPIs between 2002 and 2011. They found a 2.5-fold increased risk of acute kidney injury and a tripled increased risk of nephritis.
Aciphex and Bone Fractures
Aciphex and other PPIs may increase the risk of bone fractures — especially fractures of the hip, wrist, or spine — compared to people who do not take PPIs. This risk is greatest for people who take high doses of Aciphex, or take them for at least one year. Experts do not know exactly how Axiphex could increase the risk of bone fractures, but it is possible that the lack of acid in the stomach inhibits the body’s ability to break down calcium. This in turn decreases the amount of calcium that the body can absorb.
Safety Warnings for Bone Fractures
In April 2012, health regulators in the U.K. issued a warning about the risk of bone fractures associated with heartburn drugs. The agency warned that the increased risk of bone fractures was highest for people who had taken the drugs for more than one year. Furthermore, they warned that elderly people appeared to have the highest risk of bone fractures.
In May 2010 the FDA warned that PPIs could increase the risk of bone fractures. The warning was in response to several studies that had linked the long-term use of PPIs to an increased risk of bone fractures. The highest risk was for people who used the drug for more than one year.
- Kidney failure
- Acute Interstitial Nephritis
- Chronic Kidney Disease (CKD)
- Kidney inflammation
- Renal disease
- Bone fractures (especially of the wrist, spine, and hip)
- Low magnesium
- Tetany (muscle spasm)
- Arrhythmia and heart problems
- Stomach Cancer
Aciphex Class Action
Our law firm is nationally recognized for filing class action lawsuits, but our lawyers are not filing a class action lawsuit against the manufacturers of Aciphex. Instead, we are filing individual lawsuits and only accepting cases involving very serious injuries. If you decide to join this litigation, we may be able to help you seek compensation for your injury, medical expenses, and more.
Do I have an Aciphex Lawsuit?
The Schmidt Firm, PLLC is currently accepting Aciphex induced injury cases in all 50 states. If you or somebody you know was diagnosed with severe side effects, you should contact our lawyers immediately for a free case consultation. Please use the form below to contact our Defective Drug Litigation Group or call toll free 24 hours a day at (866) 920-0753.
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