Call Today for a FREE Confidential Case Review - Toll-Free 24/7 (866) 920-0753

Experts Say Parkinson’s Drugs May Need “Black Box” Warnings

Experts Say Parkinson’s Drugs May Need “Black Box” Warnings

October 21, 2014 — Researchers are calling for a “Black Box” warning label about pathological gambling, hyper-sexuality, compulsive shopping, and other impulse disorders on the label for drugs in the dopamine agonist class, which are commonly used to treat Parkinson’s disease and restless-leg syndrome.

The study, published in JAMA Internal Medicine, found a 277% increased risk of impulse-control disorders associated with dopamine agonists.

Requip (ripinirole) and Mirapex (pramipexole) were associated with the highest risk. A signal was also seen in patients on Abilify (aripiprazole), an anti-psychotic medication that also targets the dopamine D3 receptor.

The study suggests that 1 in 7 patients on the drugs develop psychological side effects. However, this might be a low estimate because some patients might be too embarrassed to tell their doctor about the side effect. They also may not realize the impulse disorders are a potential side effect.

According to the Wall Street Journal, researchers believe “the likelihood of a causal connection is high” and stronger warnings are needed:

“At present, none of the dopamine receptor agonist drugs approved by the FDA have boxed warnings as part of their prescribing information. Our data, and data from prior studies, show the need for more prominent warnings.”

Labels on the most popular dopamine agonists already contain warning about impulse disorders. Experts have known about the side effect for over a decade. Stronger warnings might make doctors reconsider the risks and benefits of prescribing the drugs for mild disorders, such as restless leg syndrome or hyperprolactinemia (abnormal production of milk).

Do I have an Abilify Lawsuit?

The Schmidt Firm, LLP is currently accepting dopamine agonist induced injury cases in all 50 states. If you or somebody you know has been diagnosed with an impulsive behavior disorder, you should contact our lawyers immediately for a free case consultation. Please use the form below to contact our Defective Drug Litigation Group or call toll free 24 hours a day at (866) 920-0753.

Attention Lawyers: We consider a referral from another law firm to be one of the greatest compliments. If your firm is interested in referring us a case or for us to send you a list of previous award judgments and/or average referral fees, please visit the Lawyer Referral section of our website.

Free Case Evaluation

The Schmidt Firm, PLLC has been recognized as one of the nation’s leading plaintiff’s law firms and handles cases in all 50 states. We are very proud of our legal achievements, but equally self-respecting of our firms reputation for providing personal attention to each and every client we represent.

No matter what type of case you have, you may contact us with confidence by filling out the email contact form below or calling us directly by dialing toll free 24 hrs/day (866) 920-0753.

*
*
*