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Report: Eye Damage May Continue After Elmiron is Stopped

Report: Eye Damage May Continue After Elmiron is Stopped

April 15, 2020 — Harvard researchers published a case report of a 69 year-old woman who continued to lose her vision for 6 years after stopping Elmiron®.

Dr. Rachel Huckfeldt of Harvard Medical School described the case of a woman who used a low dose of Elmiron (200-mg per day) for 18 years and developed progressive vision loss in both of her eyes.

She first developed vision loss when she was 62 years old, with blurry vision in her left eye and difficulty seeing at night.

She stopped taking Elmiron when she was 63 years old, but her vision continued to deteriorate. Six years later, at the age of 69, she returned to visit the Harvard clinic due to worsening vision loss in both eyes.

Upon examination, doctors found significantly more retinal damage. After the initial case reports of Elmiron eye diseases were published in 2018, she was diagnosed with Elmiron-associated pigmentary maculopathy.

The case report is alarming because it suggests that people who stop taking Elmiron may still suffer irreversible, progressive vision loss.

The case report “Progressive Maculopathy After Discontinuation of Pentosan Polysulfate Sodium” was published in November 2019 by the journal Ophthalmic Surgery, Lasers & Imaging Retina.

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