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Striant Blood Clot Information


The risks and benefits of long-term use of testosterone therapy are poorly understood. However, Striant has become controversial after studies found that men on testosterone therapy were more likely to have a blood clot compared to men who did not use the hormone.

What is Testosterone?

Testosterone is responsible for the normal growth and development of the male sex organs, sexual characteristics, body hair, voice, muscle and fat distribution, and more. Male hypogonadism results from low testosterone, and causes symptoms like low libido, fatigue, loss of energy, osteoporosis, mood depression, and more.

Striant and Blood Clots

The testosterone in Striant can potentially increase the risk of blood clots in the legs, also known as deep vein thrombosis (DVT). Blood clots almost always form in the calf or thigh, but they can also occur in other parts of the body.

What is the problem?

Blood clots are not always serious — many dissolve spontaneously. However, blood clots can also cause serious harm. They may grow very large and obstruct circulation, causing severe pain, swelling, and redness. They can also break loose and travel through the bloodstream (called an “embolism”) until they get stuck in a smaller blood vessel. If the blood clot is in a vital organ, it can cause a life-threatening pulmonary embolism, heart attack, or stroke.

How Can Striant Increase the Risk of Blood Clots?

  • Increasing number of red blood cells and volume of blood
  • Thickening the blood
  • Elevating blood pressure
  • Increasing circulating estrogen (risk-factor for heart disease)
  • Reducing HDL (“good”) cholesterol

What is a Blood Clot?

Blood clots are beneficial when they prevent excess bleeding after an injury. The clot is made up of platelets (a type of blood cell) and proteins in plasma (liquid part of the blood). The body naturally dissolves blood clots after the injury has healed.

What are the Symptoms of a Blood Clot?

In some cases, blood clots occur spontaneously when there is no injury. Symptoms of an abnormal blood clot may include:

  • Heart: Chest pain (often radiating to arms, neck, back, or jaw), shortness of breath, and excessive sweating.
  • Brain: Sudden visual disturbances, muscle weakness, seizures, or problems talking, or understanding speech.
  • Arms or legs: Pain, swelling, redness or discoloration.
  • Lung: Stabbing chest pain, rapid pulse, coughing up blood, sweating, nausea, fever.
  • Abdomen: Abdominal pain, vomiting, diarrhea.


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